Circadian disruption, sleep loss, and prostate cancer risk: a systematic review of epidemiologic studies.

نویسندگان

  • Lara G Sigurdardottir
  • Unnur A Valdimarsdottir
  • Katja Fall
  • Jennifer R Rider
  • Steven W Lockley
  • Eva Schernhammer
  • Lorelei A Mucci
چکیده

Disruption of the circadian system has been hypothesized to increase cancer risk, either because of direct disruption of the molecular machinery generating circadian rhythms or because of disruption of parameters controlled by the clock such as melatonin levels or sleep duration. This hypothesis has been studied in hormone-dependent cancers among women, but data are sparse about potential effects of circadian disruption on the risk of prostate cancer. This review systematically examines available data evaluating the effects of light at night, sleep patterns, and night shift work on prostate cancer risk.

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عنوان ژورنال:
  • Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

دوره 21 7  شماره 

صفحات  -

تاریخ انتشار 2012